Sheep antibody to pan synuclein: affinity purifiedS-044-100
Catalog No#: S-044-100
Product Name: Sheep antibody to pan synuclein: affinity purified
Product Type: Polyclonal Antibody
Description: Detects human alpha-, beta-, and gamma synuclein proteins. A family of homologous proteins known as alpha-, beta-, and gamma-synuclein are abundantly expressed in brain, especially in the presynaptic terminal of neurons. Although the precise function of these proteins remains unknown, alpha-synuclein has been implicated in synaptic plasticity associated with avian song learning as well as in the pathogenesis of Parkinson's disease (PD), dementia with LBs (DLB), some forms of Alzheimer's disease (AD), and multiple system atrophy (MSA).
Size: 100 ug
Applications: WB; IHC, Frozen;
Recommended Dilutions: IHC, WB. A concentration of 3 µg/mL is recommended for immunohistochemistry (frozen & paraffin embedded sections) and 1 µg/mL for western blot. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Immunogen: A synthetic peptide (AKEGVVAAAEKTKQGV) as a consensus part of human alpha-, beta-, and gamma synuclein proteins conjugated to diphteria toxoid has been used as the immunogen.
Purity: Affinity purified and dialysed against PBS. Contains 0.02% sodium azide.
Reconstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Species Reactivity: Human, Rat, other species not yet tested
Specification: Overlap specific immunohistochemical staining of alpha-, beta- and gamma synucleins | This antiserum recognises human and rat alpha-, beta- and gamma synucleins.
Shipping Conditions: 25°C (Ambient)
Storage Conditions: After reconstitution keep aliquots at -20 ºC for a higher stability, and at 4 ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Expiration Date: 12 months after purchase
Datasheet Link: http://www.biosensis.com/pdf_datasheet.php?products_id=147
Product Link: http://www.biosensis.com/product_info.php/sheep-antibody-synuclein-affinity-purified-p-147