Sheep antibody to rh NT3: IgGS-057-500
Catalog No#: S-057-500
Product Name: Sheep antibody to rh NT3: IgG
Alternative Name: Neurotrophin-3; Neurotrophic factor; HDNF; Nerve growth factor 2; NGF-2; Ntf3; Ntf-3
Product Type: Polyclonal Antibody
Description: NT3 is a member of the neurotrophin family, that controls survival and differentiation of visceral and proprioceptive sensory neurons. NT3 is closely related to both NGF and BDNF. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display sevvere movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.
Size: 500 ug
Applications: WB; IHC, Frozen; ELISA; Neut, Neutralizing
Recommended Dilutions: IHC, ELISA, WB, inhibition of biological activity. A concentration of 1-10 µg/mL is recommended for IHC, ELISA, WB and inhibition of biological activity in vitro; 2-10 µg/mL (ED50) for in vivo use. This antiserum will neutralise NT3 but not other neurotrophins. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Immunogen: Recombinant human NT3
Purity: Protein G purified IgG
Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Species Reactivity: This antiserum is known to react with Rat, Chicken and Human NT3.
Specification: A cross reactivity of less than 1% to mouse NGF, recombinant human BDNF and 5% to NT4/5 has been shown by 1-site ELISA. | This antiserum is known to react with rat, chicken and human NT3.
Shipping Conditions: 25°C (Ambient)
Storage Conditions: After reconstitution keep aliquots at -20 ºC for a higher stability, and at 4 ºC with an appropriate antibacterial agent. Glycerol (1:) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Expiration Date: 12 months after purchase
Datasheet Link: http://www.biosensis.com/pdf_datasheet.php?products_id=172
Product Link: http://www.biosensis.com/product_info.php/sheep-antibody-p-172