Sheep antibody to rh Basic FGF: affinity purifiedS-076-100
Catalog No#: S-076-100
Product Name: Sheep antibody to rh Basic FGF: affinity purified
Alternative Name: Heparin-binding growth factor 2; HBGF-2; Basic fibroblast growth factor; bFGF; Prostatropin; FGF2; FGFB
Product Type: Polyclonal Antibody
Description: Fibroblast growth factors (FGFs) bind heparin and exhibit widespread mitogenic and neurotrophic activities in a variety of different cells including mesenchymal, neuroectodermal and endothelial cells. There are differences in the tissue distribution and concentration of these 2 growth factors. aFGF (FGF-1) and bFGF (FGF-2) are present in relatively high levels in CNS. aFGF is expressed by a subset of neuronal populations, while bFGF is expressed by astrocytes, both lack signal peptides. Human bFGF is a 17.2 kDa protein containing 155 amino acid residues. FGF-2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. SUBUNIT: Monomer. Interacts with CSPG4 and FGFBP1. Found in a complex with FGFBP1, FGF1 and FGF2. MISCELLANEOUS: This protein binds heparin more strongly than does aFGF. SIMILARITY: Belongs to the heparin-binding growth factors family.
Size: 100 ug
Applications: IHC, Frozen;
Recommended Dilutions: IHC. A concentration of 1 µg/mL is recommended for immunohistochemistry. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Immunogen: Recombinant human basic FGF
Purity: Affinity purified
Reconstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Species Reactivity: This antibody is known to react with Human, Mouse and Rat basic FGF.
Specification: A high level of specificity for bFGF was shown by immunohistochemistry for this antiserum. | This antibody is known to react with human, mouse and rat basic FGF.
Shipping Conditions: 25°C (Ambient)
Storage Conditions: After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Expiration Date: 12 months after purchase
Datasheet Link: http://www.biosensis.com/pdf_datasheet.php?products_id=60
Product Link: http://www.biosensis.com/product_info.php/sheep-antibody-basic-affinity-purified-p-60