Anti-SOX 2 Monoclonal Antibody

Anti-SOX 2 Monoclonal Antibody

IHC665-100

$70.00 You Pay

Supplier: GenomeMe

Description:

SOX 2, also known as SRY (sex determining region Y)-box 2, is a transcription factor that acts to regulate pluripotency of undifferentiated embryonic stem cells, and to regulate gene expression in the stomach. This diagnostic grade SOX 2 IVD antibody is used to detect melanoma, testicular germ cell tumor, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and teratoma of the central nervous system. SOX 2 has been reported as a predictor of poor outcome in stage I lung adenocarcinomas. Anti-SOX 2 is also used to recognize squamous cell carcinomas of the lung and gastrointestinal tract, and may be useful for detecting embryonal carcinoma.

Specifications:

Clone IHC665
Source Mouse Monoclonal
Positive Control

Lung Squamous Carcinoma
Dilution Range 1:100 - 1:400

IFU & SDS:

Figure: GeneAbTM   SOX 2 [IHC665] on Cervix

References

  1. Rizzino A, et al. Wiley Interdiscip Rev Syst Biol Med. 2009; 1:228-36.
  2. Laga AC, et al. Am J Pathol. 2010; 176:903-13.
  3. Ji J, et al. Hum Pathol. 2010; 41:1438-47.
  4. Rodriguez-Pinilla SM, et al. Mod Pathol. 2007; 20:474-81.
  5. Long KB, et al. Hum Pathol. 2009; 40:1768-73.
  6. Sholl LM, et al. Appl Immunohistochem Mol Morphol. 2010; 18:55–61.
  7. Tsuta K, et al. J Thorac Oncol. 2011; 6:1190-9.
  8. Gopalan A, et al. Mod Pathol. 2009; 22:1066-74.
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