STOM Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants.
Research Areas: Cancer, Neuroscience
Applications: WB,IHC
Recommended Dilutions: WB 1:500-1:1000, IHC 1:50-1:100
Size: 200 uL
Concentration: 2mg/mL
Swissprot: P27105
Gene Accession:
Reactivity: Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant human Erythrocyte band 7 integral membrane protein
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 32 kDa
Tissue Specificity/Positive Control: Widely expressed.
Cellular Localization: Cell membrane. Cell membrane. Melanosome. Exposed on the cytoplasmic surface of the membrane. Associated with lipid rafts. Concentrates preferentially in plasma membrane protrusions and in a juxta-nuclear region which may represent Golgi-derived vesicles. Colocalizes with actin. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-stom_polyclonal_antibody-40704.html
Manual Link: https://www.elabscience.com/viewpdf-40704-elabscience-E-AB-40158.PDF