MAP2K6 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Research Areas: Cell Biology, Immunology, Signal transduction
Applications: IHC
Recommended Dilutions: IHC 1:50-1:100
Size: 200 uL
Concentration: 2mg/mL
Swissprot: P52564
Gene Accession:
Reactivity: Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant human Dual specificity mitogen-activated protein kinase kinase 6 protein
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.
Cellular Localization: Cytoskeleton,Cytosol,Nucleus,nucleoplasm,nucleus,Other locations:cytoplasm
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-map2k6_polyclonal_antibody-40713.html
Manual Link: https://www.elabscience.com/viewpdf-40713-elabscience-E-AB-40167.PDF