Oligomeric Amyloid-beta, Human, Rat, ELISA assay-1 Plate Kit

Oligomeric Amyloid-beta, Human, Rat, ELISA assay-1 Plate Kit

BEK-2215-1P

Regular price $334.74 You Pay

Supplier: Biosensis Product Type: ELISA Assay Description: The oligomeric form of Amyloid Beta peptide (A?, 1-42) has been closely linked to Alzheimer's Disease. Several ELISAs targeting A? have been developed; however, these ELISAs are known to cross-react with Amyloid Beta precursor protein (APP) and are poorly characterized against monomeric and oligomeric forms of the peptide. The Biosensis MOAB-2 antibody, developed by LaDu and co-workers (Youmans K. et al., 2012), has been shown to specifically detect A?, but not the precursor molecule APP. When utilized in ELISAs, the oligomeric form of A? peptide (o-A?) can be assayed independently of the other forms of the molecule when assayed with the MOAB-2 monoclonal antibody.

The Biosensis oligomeric A? ELISA kit is a sandwich ELISA that allows the preferential quantification of oligomeric A? peptides. This kit is exclusive to Biosensis and consists of a pre-coated mouse monoclonal anti-A? capture antibody (MOAB-2), a biotinylated MOAB-2 detection antibody and horseradish peroxidase (HRP)-conjugated streptavidin. The addition of a substrate (3,3',5,5'-tetramethylbenzidine, TMB) yields a colored reaction product which is directly proportional to the concentration of o-A? present in samples and protein standards. The purpose of this kit is the in vitro qualitative measurement of oligomeric A? peptide levels in brain extracts and CSF samples from both transgenic mice and humans relative to a known o-A? standard. The inclusion of a highly validated oligomeric standard results in a unique, ready-to-use ELISA kit.

This kit has been configured for research use only and is not to be used in diagnostic or clinical procedures. Unit Size: 1 Plate Kit Antiboy Host Species: Antibody Isotype: Applications: ELISABioActivity: Clone Name: Conjugate: Detection Method: Colorimetric Species Reactivity: Human,Rat Expiration Date: 12 months from purchase. Storage Temperature: 2-8°C Shipping Tempereature: 2-8°C (on cold packs) Product URL: www.biosensis.com/oligomeric-amyloid-beta-human-rat-elisa-assay.html