Mouse Monoclonal Antibody to KSHV ORF820043
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Immunogen: Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8. ;
Formulation: Rabbit anti-serum.
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=72
Reference: 1. James J. Proc. Natl. Acad. Sci Vol. 1993, pp. 14862-14867. ; 2. Wang FZ. J Virol. 2003 Mar; 77(5):3131-47. ;