Figure 1: Western blot analysis using LAL mouse mAb against LAL recombinant protein.

Mouse Monoclonal Antibody to LAL

20061

Regular price $264.00 $224.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 9G7F12;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of LAL expressed in E. Coli.
Formulation: Purified antibody in PBS containing 0.03% sodium azide.
MW: N/A
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=86
Reference: 1. Uta Drebber, Matthias Andersen, Hans U Kasper, et al, World J Gastroenterol. 2005 Apr 21;11(15):2364-6. ; 2. Renata Boldrini, Rita Devito, R.Biselli,et al, Pathol Res Pract. 2004;200(3):231-40. ;