Figure 1: Western blot analysis using ERK2 mouse mAb against Hela (1), NIH/3T3 (2), MCF-7 (3), HEK293 (4), Jurkat (5), A549 (6), NTERA-2 (7) and SMMC-7721 (8) cell lysate.

Mouse Monoclonal Antibody to ERK2

20092

$264.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: ERK2 (also designated extracellular-signal-related kinase 2 or mitogen-activated protein kinase 1), with 360-amino acid protein (about 40kDa), belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Monkey
Clone: 4C11;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human ERK2 expressed in E. Coli.
Formulation: Purified antibody in PBS containing 0.03% sodium azide.
MW: 41kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=112
Reference: 1. Angelique W. Whitehurst, Fred L. Robinson, Mary Shannon Moore. J. Biol. Chem., Mar 2004; 279: 12840 – 12847. ; 2. N Hatano, Y Mori, M Oh-hora. Genes Cells, Nov 2003; 8: 847 - 856. ;

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