Mouse Monoclonal Antibody to PR

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: PR(progesterone receptor), with 933-amino acid protein (about 110kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2F12B4;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of PR expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: N/A
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=124
Reference: 1. McGuire, W.L., et al. 1986. Cancer.Surv.5:527-536. ; 2. Helena CD, Curt WB, Paul V,et al. 2000. J.Clin. Pathol. 53:201-205. ; 3. Wen, D.X., et al. 1994.Mol.Cell.Biol.14:8356-8364. ; 4. GM Clark, CK Osborne, WL McGuire.1984.J. Clin. Oncol., 2:1102-1109. ;

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