Figure 1: Western blot analysis using survivin mouse mAb against full-length survivin recombinant protein (1) and full-length survivin-GFP transfected Cos7 cell lysate (2).

Mouse Monoclonal Antibody to Survivin


Regular price $308.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2H5H2;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of Survivin expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
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Reference: 1. Urology. 2007 Sep;70(3):482-6. ; 2. World J Gastroenterol. 2007 May 28;13(20):2784-90. ; 3. Histopathology. 2007 Jun;50(7):835-42.

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