Mouse Monoclonal Antibody to LPP

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: LIM domain containing preferred translocation partner in lipoma. The Zyxin family of proteins contains five members, Ajuba, LIMD1, LPP,TRIP6 and Zyxin. LPP (LIM-containing lipoma-preferred partner), a LIM domain-containing scaffolding protein contains three LIM domains at its carboxy terminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. LPP, an 80 kDa protein, localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts,and shuttles to the nucleus where it has transcriptional activation capacity.The human LPP gene maps to chromosomal location 3q28, and preferentially translocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Monkey; Hamster
Clone: 8B3A11;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human LPP expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 66kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=188
Reference: 1. BMC Cell Biol. 2005 Jan 13;6(1):1 ; 2. Mol Cell Proteomics. 2005 Sep;4(9):1240-50. Epub 2005 Jun 11. ; 3. Cancer Genet Cytogenet. 2005 Nov;163(1):68-70. ;

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