Mouse Monoclonal Antibody to EhpB620183
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: EhpB6: EPH receptor B6. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of EphB6 (aa601-750) expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=193
Reference: 1. J Clin Invest. 2002 Oct;110(8):1141-50. ; 2. J Biol Chem. 2002 Feb 8;277(6):3823-8. Epub 2001 Nov 16. ; 3. J Biol Chem. 2003 Mar 21;278(12):10150-6. Epub 2003 Jan 6. ; 4. Biochem Biophys Res Commun. 2006 Feb 3;340(1):268-76.
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