Figure 1: Western blot analysis using PBEF1 mouse mAb against truncated PBEF1-His recombinant protein (1) and full-length GFP-PBEF1(aa1-491) transfected COS7 cell lysate (2).

Mouse Monoclonal Antibody to PBEF1

20188

Regular price $264.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1D3A12;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: N/A
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=197
Reference: 1. Mol Cell Biol. 1994 Feb;14(2):1431-7. ; 2. Eur J Immunol. 2002 Nov;32(11):3225-34.

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