Mouse Monoclonal Antibody to APOA1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: APOA1: apolipoprotein A-I, it is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5F4F5;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human APOA1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 25kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=200
Reference: 1. J Mol Med. 2006,Jul, 84(7):561-72. Epub 2006 May 17. ; 2. Clin Endocrinol (Oxf). 2006,Mar, 64(3):260-4.

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