Mouse Monoclonal Antibody to EphB3

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: EphB3: EPH receptor B3. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4A122D1;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of EphB3 (aa39-212) expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: N/A
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=203
Reference: 1. Oncogene. 1998 Jan 29;16(4):471-80. ; 2. Pharmacol Ther. 1998 Mar;77(3):151-81. ; 3. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9779-84. ; 4. J Biol Chem. 2002 Jun 21;277(25):23037-43.

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