Mouse Monoclonal Antibody to Glucose-6-phosphate isomerase

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Glucose-6-phosphate isomerase, or phosphoglucose isomerase, also known as GPI. It belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1B7D7;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human GPI expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 63kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=205
Reference: 1. Biochem Biophys Res Commun. 2004 Oct 15;323(2):518-22. ; 2. Biochem Biophys Res Commun. 2006 Oct 20;349(2):838-45. ; 3. Hum Mutat. 2006 Nov;27(11):1159. ; 4. Leuk Lymphoma. 2006 Oct;47(10):2234-43.

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