Figure 1: Immunofluorescence analysis of Hela (Left) and MCF-7 (Right) cells using Tyro3 mouse mAb (green).

Mouse Monoclonal Antibody to Tyro3


Regular price $308.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
Application: ELISA: 1/10000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 6D6F10;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
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Reference: 1. Christoph Heiring, Bjon Dahlbok, and Yves A. Muller. J. Biol. Chem Feb 2004; 279: 6952 - 6958. ; 2. Sassan Hafizi, Anna Gustafsson, Jonas Stenhoff. Int J Biochem Cell Biol. 2005 Nov;37(11):2344-56. ;

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