Mouse Monoclonal Antibody to GABPA

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: GABPA: GA binding protein transcription factor, alpha subunit 60kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse
Clone: 8C1B10;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human GABPA (aa120-190) expressed in E. Coli. ; ;
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: 51kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=228
Reference: 1. Science. 1998 Feb 13;279(5353):1037-41. ; 2. J Biol Chem. 1999 Dec 10;274(50):35475-82. ; 3. EMBO J. 2000 Feb 15;19(4):683-90. ; ;

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