Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: KARS: lysyl-tRNA synthetase. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of KARS(aa90-174) expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=235
Reference: 1. J Biol Chem. 2000 Nov 10;275(45):35063-9. ; 2. J Virol. 2001 Jun;75(11):5043-8. ; 3. Biochem Biophys Res Commun. 2002 Feb 15;291(1):158-64. ; 4. Cell. 2004 Oct 15;119(2):195-208.