Mouse Monoclonal Antibody to AXL20250
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: AXL: AXL receptor tyrosine kinase. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=243
Reference: 1. Nature. 2005 Oct 20;437(7062):1173-8. ; 2. Mol Cell Biol. 2005 Nov;25(21):9324-39. ; 3. Circ Res. 2007 Mar 2;100(4):502-9.