Figure 1: Western blot analysis using HDAC3 mouse mAb against Hela (1), NIH/3T3 (2), C6 (3) and COS (4) cell lysate.

Mouse Monoclonal Antibody to HDAC3


Regular price $352.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7G6C5;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 48.8kDa
Storage: 4C; -20C for long term storage
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Reference: 1. Folia Biol (Praha). 2006;52(1-2):21-33. ; 2. Mol Cell Biol. 2007 Feb;27(4):1280-95. ; 3. Mol Carcinog. 2008 Feb;47(2):137-47.

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