Mouse Monoclonal Antibody to NCOR1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: NCOR1: Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7A7A9;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: N/A
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=256
Reference: 1. Mol Cell Biol. 2005 Aug;25(15):6404-14. ; 2. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1471-80.

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