Mouse Monoclonal Antibody to PGR20268
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of PGR (aa730-871) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=259
Reference: 1. Cancer Sci. 2006 Dec;97(12):1308. ; 2. Mol Endocrinol. 2006 Nov;20(11):2656-70. ; 3. Mol Endocrinol. 2007 Jan;21(1):106-25. ; 4. J Clin Endocrinol Metab. 2007 Nov;92(11):4459-66.