Mouse Monoclonal Antibody to NCOA320274
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: NCOA3: nuclear receptor coactivator 3. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of NCOA3 (aa1-200) expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=265
Reference: 1. Mol Cell Biol. 2005 Sep;25(18):8273-84. ; 2. J Clin Oncol. 2006 Oct 1;24(28):4565-9.
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