Mouse Monoclonal Antibody to CD44

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: CD44, also known as IN, LHRMIC4, CDW44, HCELL. It is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human, Mouse
Clone: 8E2F3;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CD44 (628-699) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: 82kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=271
Reference: 1. Exp Mol Pathol. 2007 Dec;83(3):341-6. ; 2. Mol Cell Proteomics. 2008 Mar;7(3):499-508.

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