Mouse Monoclonal Antibody to CHIT120302
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=291
Reference: 1. Sarcoidosis Vasc Diffuse Lung Dis. 2007 Mar;24(1):59-64. ; 2. Clin Biochem. 2007 Mar;40(5-6):365-9.