Figure 1: Western blot analysis using CHIT1 mouse mAb against truncated Trx-CHIT1 recombinant protein (1) and truncated CHIT1 (aa22-466)-hIgGFc transfected CHO-K1 cell lysate (2).

Mouse Monoclonal Antibody to CHIT1


Regular price $308.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1D9G2;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
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Reference: 1. Sarcoidosis Vasc Diffuse Lung Dis. 2007 Mar;24(1):59-64. ; 2. Clin Biochem. 2007 Mar;40(5-6):365-9.

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