Mouse Monoclonal Antibody to SOD1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse
Clone: 6F5;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human SOD1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 18kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=329
Reference: 1. Apoptosis. 2005 May;10(3):499-502. ; 2. Hum Mol Genet. 2008 Nov 1;17(21):3303-17.

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