Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Application: ELISA: 1/10000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of RTN3 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=337
Reference: 1. Biochem Biophys Res Commun. 2005 Sep 9;334(4):1198-205. ; 2. Brain Res Mol Brain Res. 2005 Aug 18;138(2):236-43. ; 3. FASEB J. 2003 Jul;17(10):1238-47.