Mouse Monoclonal Antibody to Proteinase 320373
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
Formulation: Antibody are purified by protein G affinity chromatography. ; Liquid in PBS containing 50% glycerol and 0.03% sodium azide. ;
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=349
Reference: 1. Blood. 2007 Dec 1;110(12):4086-95. ; 2. Clin Exp Immunol. 2006 Jul;145(1):63-70.
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