Mouse Monoclonal Antibody to TEC

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3A5;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of TEC expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 74kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=355
Reference: 1. Blood. 2000 Nov 15;96(10):3406-13. ; 2. J Biol Chem. 1999 Jan 8;274(2):607-17. ; 3. Blood. 1998 Feb 1;91(3):940-8. ;

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