Mouse Monoclonal Antibody to OCT4

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in protein-protein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation. Oct4 is renowned as a transcription factor expressed by undifferentiated embryonic stem cells and embryonic germ cells.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3A5;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of OCT4 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 39kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=358
Reference: 1. Stem Cells. 2009 Mar;27(3):543-9. ; 2. Genome Biol. 2008;9(12):R172.

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