Mouse Monoclonal Antibody to FABP420409
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of FABP4 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=375
Reference: 1. Proc. Natl. Acad. Sci. 2006.103:6970–75. ; 2. Science. 1996. 274:1377–79. ; 3. Biochemistry. 1997.36(27):8311-7 ; 4. Mol Cell Biochem. 2004.302(1-2):203-13 ;