Figure 1: Western blot analysis using KRT15 mouse mAb against A431 cell lysate.

Mouse Monoclonal Antibody to KRT15

20410

Regular price $308.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 6E7;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of KRT15 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 49kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=376
Reference: 1. J Invest Dermatol. 1999. 112(3):362-9 ; 2. Exp Cell Res. 2006. 254(1):80-90 ; 3. Mol Cell Biol. 2000. 24(8):3168-79

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