Mouse Monoclonal Antibody to FABP2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 9A9B7B3;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human FABP2 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 15kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=382
Reference: 1. Yamada, K. et al. (1997) Diabetologia. 40(6):706-10 ; 2. Georgopoulos, A. et al. (2000)85(9):3155-60 ; 3. Kim, CH. et al. (2001) Metabolism. 50(4):473-6 ; 4. Fisher, E. et al. (2006) Horm Metab Res. 38(5):341-5

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