Mouse Monoclonal Antibody to CHD320422
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CHD3 expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=388
Reference: 1. Virus Res. 2003 Dec;98(1):83-91. ; 2. Mol Cell. 2004 Sep 24;15(6):853-65. ; 3. J Biol Chem. 2008 Dec 12;283(50):34976-82.
Note: Highly recommend to send quote request for product availability and estimated shipping charge