Mouse Monoclonal Antibody to Androgen receptor

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2H8;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human AR expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: 110kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=407
Reference: 1. Chin Med J (Engl). 2009 Nov 20;122(22):2779-83. ; 2. Taiwan J Obstet Gynecol. 2009 Sep;48(3):262-7. ; 3. Prostate. 2008 Mar 1;68(4):453-61. ; 4. Cancer Res. 2007 May 15;67(10):4630-7.

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