Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Monkey
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human DKK3 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=410
Reference: 1. Virchows Arch. 2009 Jun;454(6):639-46. ; 2. Gene. 2002 Jan 9;282(1-2):151-8. ; 3. J Urol. 2004 Mar;171(3):1314-8.