Mouse Monoclonal Antibody to CK7

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5D12;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CK7 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 51kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=413
Reference: 1. Cytogenet Cell Genet. 1991;57(1):33-8. ; 2. J Pathol. 1998 Mar;184(3):234-9. ; 3. J Cell Biol. 2006 Jul 17;174(2):169-74.

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