Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Synthetic peptide of human PARP, conjugated to KLH.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=416
Reference: 1. Cytogenet Cell Genet. 1992;61(3):172-4. ; 2. J Immunol. 1997 Dec 1;159(11):5246-52. ; 3. J Biol Chem. 2001 Dec 7;276(49):45588-97.