Mouse Monoclonal Antibody to CDC25C

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1F12;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CDC25C expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: 58kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=422
Reference: 1. Cancer Cell. 2007 Mar;11(3):275-89. ; 2. Int J Biochem Cell Biol. 2007;39(9):1707-13. ; 3. Int J Cancer. 2010 May 1;126(9):2199-210.

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