Mouse Monoclonal Antibody to ALPP

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3E5;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human ALPP expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: 58kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=461
Reference: 1. J Cell Biochem. 2003 Apr 1;88(5):1025-37. ; 2. J Mol Biol. 2005 Jul 15;350(3):441-51.

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