Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Rat; Monkey
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human STAT6 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=468
Reference: 1. Pediatr Nephrol. 2009 Mar;24(3):489-95. ; 2. Mol Immunol. 2009 Jun;46(10):2080-9. ; 3. Am J Hum Genet. 2009 Nov;85(5):628-42.