Mouse Monoclonal Antibody to NFKBIB30082
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human NFKBIB expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=482
Reference: 1. Mol Cell Biol. 2004 Apr;24(7):3048-56. ; 2. J Biol Chem. 2004 Oct 15;279(42):44030-8. ; 3. J Bone Miner Res. 2009 Dec;24(12):2039-49.