Mouse Monoclonal Antibody to PTH1R

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4D2;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PTH1R expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 66kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=485
Reference: 1. Int J Cancer. 2007 Sep 1;121(5):943-54. ; 2. Mol Endocrinol. 2008 Jan;22(1):156-66.

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