Mouse Monoclonal Antibody to COX4I1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Cytochrome c oxidase (COX) functions as the terminal oxidase of the respiratory chain that uses cytochrome c as an electron donor to drive a proton gradient across the inner mitochondrial membrane. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial encoded catalytic subunits and several nuclear gene encoded structural subunits. COX contains two iron-coordination sites and two copper-coordination sites. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Monkey; Rat; Mouse
Clone: 6B3;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human COX4I1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 19kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=495
Reference: 1. Biochim Biophys Acta. 1992 Feb 26;1119(2):218-24. ; 2. Histochemistry. 1990;94(2):211-5. ; 3. FEBS Lett. 2000 Jun 30;476(1-2):22-6.

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