Mouse Monoclonal Antibody to ESR1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 6B6;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human ESR1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 66kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=498
Reference: 1. Calcif Tissue Int. 2010 Jul;87(1):25-35. ; 2. Arch Gynecol Obstet. 2010 Jun 18. ; 3. Biochemistry. 2010 Jul 27;49(29):5978-88.

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