Mouse Monoclonal Antibody to EIF2AK330115
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=514
Reference: 1. Autophagy. 2008 Apr 1;4(3):364-7. ; 2. J Biol Chem. 2008 Jun 20;283(25):17020-9. ; 3. Hum Mol Genet. 2008 Oct 15;17(20):3254-62.