Mouse Monoclonal Antibody to CDKN1C

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3E3;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CDKN1C expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: 57kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=529
Reference: 1. Cell Cycle. 2007 Mar 1;6(5):620-5. ; 2. Oncogene. 2008 Sep 25;27(43):5651-61.

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